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No regulator has evaluated the safety or effectiveness of pill or oral versions of tirzepatide. Lilly also reiterates that Mounjaro and Zepbound are approved only for use by adults to treat serious diseases, they are not intended for cosmetic weight loss or use by people under 18

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Margaret Osborne, a clinician with a special interest in weight management, delineates, "Non-adherence or erratic adherence to Wegovy not only stymies the potential weight loss but may also engender a physiological environment that obfuscates the clear assessment of the medications true impact and safety in the individual context" (Osborne, 2022)

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