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9 In light of the important contribution of the incretin effect to prandial insulin release, augmentation of this system in people with T2DM has been shown to be an important pharmacologic approach to glycemic management
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this, in turn, resulted in the upregulated expression of telomere repeat-binding factor 1/2 (TRF1/TRF2) proteins and strict dependence on p53/p21 signaling, followed by irreversible G2/M cell cycle arrest, ultimately leading to apoptosis
If you become pregnant while on treatment, stop the medication immediately and contact your healthcare provider
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