glp-1 kidney Frontiers ICYMI: GLP-1 Agonists Show Promise

The benzyl alcohol inhibits the growth of most bacteria, allowing the solution to be used multiple times in a research setting without contamination

They tested two doses: 10 g/kg and 10 ng/kg (that is a thousand times less!)

Cortisol levels are still elevated above evening baseline, preserving partial circadian receptor advantage while shifting nausea into late afternoon rather than sleep onset

Moreover, lixisenatide is a short-acting GLP-1RA with a half-life of ~3 h, suggesting an estimated daily engagement of GLP-1 receptors (GLP-1R) of ~14 h that could have possibly hampered the detection of its protective effects [10]