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doi: 10.1016/j.febslet.2005.03.044 14 El-SalhyMHatlebakkJGHauskenT

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When mitochondrial function is impaired, it can lead to reduced energy availability, oxidative stress, and contributes to a range of metabolic disorders, including insulin resistance and obesity

Ding X, Saxena NK, Lin S, Gupta NA, Anania FA (2006) Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice