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The results are very interesting and indicate a new mechanism of action for tirzepatide and suggest a potential new mechanism for BAT activation. When Obesity Cant Wait: Treating Metabolic Disease in Early Childhood In Type 2 Diabetes in a 4-Year-Old With Obesity: Considerations for Use of Semaglutide and Bariatric Surgery in Children , published in JCEM Case Reports in July, Alaina Vidmar, MD, medical director, Obesity Medicine, and Bariatric Surgery at Childrens Hospital Los Angeles in California and team describe a case they believe may help other clinicians treat the growing population of very young children with similar conditions