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Most people with MTHFR gene mutations dont have any symptoms

I often say that Gut microbiome diversity is like the Holy Grail of our health. This biodiversity is associated with positive health outcomes, including lower inflammation and reduced risk of chronic diseases

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Importantly, they can also convert indigestible carbohydrates into short-chain fatty acids (SCFA), which in turn activate specific G protein-coupled fatty acid (FFA) receptors, thereby promoting the secretion of peptide hormones from the enteroendocrine cells [106, 107]