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Instead of taking B12 supplements, it is possible to get sufficient amounts from B12-fortified foods, but we would have to eat three servings a day of foods each providing at least 85 percent of the Daily Value (on the Nutrition Facts label), with each serving eaten at least four to six hours after the last (the target is 2 mcg three times a day)

Semaglutide Citations: SUSTAIN Clinical Trial Series: A comprehensive series of studies evaluating the efficacy and safety of Semaglutide in patients with type 2 diabetes, highlighting its impact on glycemic control, weight loss, and cardiovascular outcomes

That reach is a big part of why it's attracted so much attention in the wellness space

Beutler, E., Blood , 14 , 103 (1959)