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All three GLP-1 analogs also reduced systolic and diastolic blood pressure [17,19,76]

Antihypertensive medications (Moderate interaction - monitor): L-Arginine and L-Citrulline may lower blood pressure through nitric oxide-mediated vasodilation

New Safety Signal: Dysesthesia The TRIUMPH-4 trial identified a previously unreported side effect called dysesthesia an abnormal sensation of touch where normal sensations feel unusual, uncomfortable, or mildly painful (like tingling, numbness, or "pins and needles")

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