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Yes, particularly in older adults

These drugs: reduce appetite increase satiety slow stomach emptying improve insulin signaling lower post-meal glucose spikes have massive and long-lasting side effects as listed above The newer medications, such as tirzepatide, also activate GIP receptors in addition to GLP-1 receptors, which may further enhance weight loss and glucose control

The worldwide prevalence of diabetes has continued to increase dramatically instead of the improvement in outcomes for individual patients with diabetes