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CYP2E1 enzymes work in the mitochondria and endoplasmic reticulum in response to high ethanol levels, and this produces a lot of ROS and oxidative stress.[ref][ref] Related article : CYP2E1 gene variants | Alcohol use disorder Calcium signaling and mitochondria: In addition to their vital role in cellular energy production, mitochondria also participate in signaling between cells using calcium ions

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In both the SVZ and the SGZ, the most undifferentiated stem cells (type B) are a subset of glial astrocytes in terms of their structural and electrophysiological properties (Riquelme et al., 2008)