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During rapid weight loss, follicles that were in the active growth phase (anagen phase) abruptly transition to the shedding phase (telogen phase)

These compounds exhibit anti-proliferative, anti-inflammatory, anti-angiogenic, anti-oxidant and pro-apoptotic activities [12,13,14,15]

Supporting Evidence A 2025 systematic review and meta-analysis of nearly 29,000 patients across observational studies and randomized trials found tirzepatide produced significantly greater weight reduction than semaglutide, with notably higher odds of achieving at least 10% weight loss

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