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Increases of roughly up to ~30 minutes above an individual's 7-day baseline showed little change in recovery metrics, but larger jumps in training load were associated with higher minimum heart rate and persistently lower HRV

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What FDA Interchangeable Biosimilar Designation Requires and Which Products Have Achieved It Under Section 351(k) of the Public Health Service Act, a biosimilar can receive interchangeable designation if it meets biosimilarity criteria and demonstrates, via switching studies, that alternating between the biosimilar and the reference product produces no greater safety or efficacy risk than continued use of the reference product

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R., Rottmann M., Tan L

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