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Its multifaceted actions contribute to its neuroprotective and cognitive-enhancing properties, making it a well-established therapy for brain health and healing in various clinical contexts

These metabolites can modulate bloodbrain barrier permeability, microglial activation, and neurotransmitter release, impacting both brain function and behavior [48, 49]

In a mixed model ANCOVA, the pretreatment TEE depended on BW, but also on experiment (adjusted (coefficient of determination) R 2 = 0.471, 68% of attributable variation due to BW and 32% to experiment)

In order to elucidate the inhibition mechanism of HQ, we solved two crystal structures of TyrBm with HQ in the active site