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Behavioral intervention involved counseling by a dietitian or equivalent healthcare professional every 4 weeks through in-person visits or telephone sessions, focusing on adhering to a reduced-calorie diet (500 kcal deficit per day compared to estimated energy expenditure at randomization) and increased physical activity (encouraging 150 minutes per week, such as walking), with daily recording (via diary, app, or other tools) reviewed during counseling sessions

Rodrigues M, Kosaric N, Bonham CA, Gurtner GC

This helps deliver more nutrients to the lower small intestine and colon, where GLP1producing cells are concentrated (6)

Kojic Acid: Supports skin brightening routines and helps improve the appearance of uneven skin tone