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The S protein produced by these vaccines binds to ACE2, leading to its downregulation, which has been found to induce the release the IL-1 and IL-6 (97)

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Comment: Most commenters supported our proposal to effectuate full realignment of the IPPS and OPPS wage index values in CY 2026 by eliminating the low wage index hospital policy under the OPPS and using the IPPS wage index in CY 2026 and subsequent years