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GLP-1R is a core member of the G protein-coupled receptor family and is widely distributed on the surface of many human cells (Zheng et al., 2024)

Following peripheral nerve injury, GLP-1R expression is upregulated in microglial cells of the spinal dorsal horn [31]

The national organization, Americas Poison Centers, has also reported a dramatic spike, with a nearly 1500% increase in calls related to injectable weight loss drugs since 2019

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