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Obesity is also associated with a pro-inflammatory state marked by elevated levels of cytokines such as TNF-, IL-6, and prostaglandin E2, which promote tumor proliferation, invasion, angiogenesis, and immune evasion [4,20]

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Vitamin B12 Deficiency People most at risk for vitamin B12 deficiency include those over the age of 65, vegans and vegetarians (who often dont eat enough animal products), people who have gastrointestinal diseases like Crohns disease or celiac disease, and anyone who has had part of their gastrointestinal tract removed through gastric bypass or another type of surgery, Wright says