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Amylin analogues long-acting compounds investigated for how they complement incretin signalling

Weight loss medications have gained a lot of attention over the last few years

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The two fusion proteins were designed with either an intact C-terminal end (GLP-1 WT and GLP-1 QMP) or a truncated end lacking L585 (GLP-1 LX and GLP-1 QMP/LX) (Fig