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Medical Conditions, Surgeries, and Medications Lack of intrinsic factor (a protein made in the stomach thats needed for B12 absorption) - this condition is called pernicious anemia Thyroid disease HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome) Autoimmune diseases like type 1 diabetes, where the immune system in the body attacks its own tissues Gastric bypass surgery (weight loss surgery) Chronic gastritis surgery Certain medications like heartburn drugs (proton pump inhibitors) which reduce stomach acid production Who Is At Risk of Vitamin B12 Deficiency
Since then, numerous studies have been done to understand the GPx-like catalytic mechanism of ebselen and to test its potential as a therapeutic invention for preventing or treating oxidative stress-related disorders [76]
Sampling and biochemical data collection After an overnight fasting of at least 12 h, blood samples were collected by venipuncture using BD Vacutainer EDTA tubes
Management also includes CT or MRI to rule out optic neuropathy from compression related to the enlargement of the extraocular muscles
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