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[22] B 12 deficiency in pregnant women is increasingly common [23] and has been shown to be associated with major maternal health implications, including increased obesity, [23] higher body mass index (BMI), [24] insulin resistance, [22] gestational diabetes, and type 2 diabetes (T2D) in later life

MT1 is frequently studied for its apparent preference toward MC1R, a receptor expressed predominantly in melanocytes and linked to melanin synthesis pathways

Inhibition of the NMDA receptor, which is a ligand-activated Ca 2+ channel, decreases this phosphorylation, which could explain the cognitive deficits induced by ketamine due to the disruption of long-term potentiation (72)

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