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This study is the first, to our knowledge, to report an association between semaglutide and NAION, although the design of our study did not enable query into a causal relationship between the two, the researchers wrote in their findings, published Wednesday in the journal JAMA Ophthalmology

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Why GLP-1 Side Effects Happen GLP-1-based medications affect appetite signaling, satiety, digestion, and how food moves through the stomach and intestines