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This condition disrupts energy balance, leads to drastic metabolic changes, and causes a notable decrease in fat mass and apparent skeletal muscle atrophy due to perturbing proinflammatory cytokines

Introduction The pre-proglucagon (Gcg) gene product peptides include glucagon-like peptide 1 (GLP-1), GLP-2, oxyntomodulin (OXM), intervening peptide 1 (IP1), and glicentin