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They designed a 16-week prospective randomized open-label study with 30 men, with BMI 41.2 8.4 kg/m2 and aged 46.5 10.9 years

Semaglutide has the longest safety record and the SELECT trial proving cardiovascular benefits

[5] [8] Animal studies have shown thyroid C-cell tumours (medullary thyroid carcinoma) with some GLP-1 receptor agonists, but there is no confirmed link in humans and this is not a formal contraindication in UK prescribing information

Inulin supplementation may alleviate hepatic steatosis by increasing adipose triglyceride lipase activity on hepatic lipid droplets and inhibiting expression of cannabinoid receptor-1 and patatin-like phospholipase-3 in the liver (110, 111)