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Catalpol also alleviates oxidative stress in diabetic rats, potentially through inhibition of oxidized low-density lipoprotein (oxLDL)/LDL and NF-B signaling pathways, thereby mitigating macroangiopathy induced by a high-fat and high-sugar diet combined with STZ in type 2 diabetic rats (Luo et al., 2023)

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By supporting normal mitochondrial activity, DSIP could potentially reduce metabolic injury and preserve tissue stability until circulation is restored

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