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You should also avoid semaglutide if youre pregnant

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Some patients regain part of the weight after treatment ends because appetite and hunger signals can return

Consequently, new theories around the modes of action for SGLT2 inhibitors and GLP-1 RAs are being hypothesised [112, 117,118,119], although as yet it remains unclear which mechanism(s) are responsible, or whether there is any mechanistic overlap between cardiorenal benefits with SGLT2 inhibitors and GLP-1 RAs