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As protein-based biologics, they are extremely sensitive to temperature deviations: Too Cold (below +2 C): Freezing causes proteins in GLP-1 drugs to denature, making the batch unusable and resulting in immediate financial loss

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Further reinforcing this early and rapid inflammation reduction is that a lab measure called hsCRP, or high sensitivity C-reactive protein, was significantly reduced at 4 weeks as well, when patients had only lost 2.7% of their body weight

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