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While historically listed with an "unknown status," recent data releases in late 2025 and early 2026 have clarified the safety profile that helped justify the Category 1 reclassification. Study Design: A randomized, placebo-controlled, double-blind Phase 1 pilot study

Additionally, patients who struggle with severe metabolic adaptationwhere their resting metabolic rate has plummeted following initial weight lossoften respond well to the sympathetic nervous system stimulation provided by this compound

And it's actually prescribed for what's called hypothalamic amenorrhea

Dorantes began her career as a Beauty Advisor for Estee Lauder