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NICE NG69 specifically cautions against placing individuals with BED on calorie-restricted diets as a standalone treatment

Important safety considerations for paracetamol use: Check all medications for paracetamol content, as it is included in many combination cold and flu remedies Individuals with liver disease, chronic alcohol use, malnutrition, or low body weight may need lower maximum doses - seek advice from a healthcare professional Paracetamol is generally safe in pregnancy and breastfeeding when used at recommended doses If you accidentally take more than the recommended dose, seek immediate medical attention via NHS 111 or A&E, even if you feel well Regular paracetamol use may increase INR in patients taking warfarin - consult your healthcare professional if you need regular pain relief For people with type 2 diabetes taking Rybelsus, paracetamol remains an appropriate choice for pain relief and fever management

Lett Appl Microbiol

LRRK2 regulates CPT1A to promote beta-oxidation in HepG2 cells