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Effective management includes gentle skincare, appropriate topical treatments, lifestyle adjustments, and seeking professional care when necessary

It has been suggested to promote organized collagen formation, enhance fibroblast activity (cells crucial for connective tissue repair), and improve the mechanical strength of repaired tissues

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each R 4 is independently selected from F, Cl, Br, I, CN, NO 2 , CF 3 , OR 9 , OCF 3 , NR 8 R 9 , C(O)R 10 , CO 2 R 9 , C(O)NR 8 R 9 , N(R 8 )C(O)R 10 , N(R 8 )CO 2 R 10 , NHS(O) 2 R 10 , S(O) 2 NR 8 R 9 , C 3 -C 6 cycloalkyl, C 1 -C 6 heteroalkyl, C 1 -C 6 haloalkyl, C 2 -C 7 heterocycloalkyl, C 6 -C 10 aryl, and C 3 -C 9 heteroaryl