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I had similar issues, though not as drastic as yours

And while its true that a B12 deficiency can contribute to those things, there is one problem, says Ashley Barrient, a clinical dietitian at the Loyola Center for Metabolic Surgery & Bariatric Care in Chicago: Most of us arent deficient

While originally isolated for its ability to promote slow-wave (deep) sleep, subsequent research has revealed DSIPs potential in influencing multiple physiological systems, including neuroprotection, hormone regulation, and pain modulation

Combining the two pathways is what makes the pairing potentially more effective than either drug on its own