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Supportive commenters stated that the Type 2 NPI is a valuable identifier for linking to claims data and provider directories, and the inclusion of this information in the MRF would enhance interoperability across datasets, including TiC files

NICE Clinical Knowledge Summaries and British Society for Haematology guidelines emphasise the importance of prompt investigation when clinical features suggest deficiency

Stephanie Weiss, M.D., Ph.D., assistant director for the Clinical Research, Medication Development Program at NIDA, shared data from the first published clinical trial of GLP-1 RAs in alcohol use disorder: in patients with obesity with a BMI over 30, exenatide reduced heavy drinking days by 23.6% and lowered total alcohol intake

This reduces systemic drug exposure and minimizes adverse effects