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Primary Endpoint: Weight Loss at 72 Weeks The results were striking and clinically significant: Zepbound Group: Participants achieved an average weight reduction of 20.2% at 72 weeks Wegovy Group: Participants achieved an average weight reduction of 13.7% at 72 weeks Relative Difference: Zepbound provided 47% greater relative weight loss compared to Wegovy To put this in practical terms: A patient weighing 250 pounds could expect to lose approximately 50 pounds with Zepbound versus 34 pounds with Wegovy over the same timeframe
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It's important to note that while Wegovy (semaglutide 2.4 mg) is approved for weight management, Ozempic (semaglutide) is FDA-approved only for type 2 diabetes treatment, not for weight loss
Tirzepatide with niacinamide Niacinamide (vitamin B3) is added by some pharmacies for its potential insulin-sensitizing effects and as a stabilizer
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