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Clinical trials in diabetic ulcer patients have reported 25-40% reductions in wound inflammatory markers when GHK-Cu-containing formulations are applied as adjunctive therapy to standard wound care protocols

Results depend on baseline B12 status

The AEOL series (named after Aeolus Pharmaceuticals

In melanoma studies, ubiquitin specific peptidase 22 controls melanoma metastasis and sensitivity to ferroptosis through the SIRT1/phosphatase and tensin homolog deleted on chromosome 10 (PTEN)/phosphoinositol-3 kinase (PI3K) signaling pathway, suggesting that activation of the SIRT1 pathway may enhance melanoma cells sensitivity to ferroptosis (Sun et al., 2024)