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Name: tirzepatide maximum weight loss surmount trials once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial Tirzepatide for the Maintenance of
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Shim et al

10.1016/s2213-8587(18)30268-7 57 NielsenM

By lowering inflammatory markers and oxidative stress

Acetaminophen affects the brain compared to opioids by inhibiting pain signals in the central nervous system , but it does not directly affect the brains reward system like opioids