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Unlike older medications, tirzepatide leverages dual action: reducing appetite, slowing digestion to prolong fullness, improving insulin sensitivity, and potentially boosting calorie burning

These are predominantly related to gastrointestinal tract, namely nausea, diarrhea, and vomiting as well as constipation and gastroparesis [122], while there is also some evidence of gallbladder-associated adverse effects due to rapid loss of body weight [122,123]

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