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This rapid deterioration of -cell function is more rapid in children when compared to adults with T2D ( Several conditions are associated with T2D including obesity, dyslipidemia, hypertension, obstructive sleep apnea, polycystic ovary syndrome, and non-alcoholic fatty liver disease ( T2D impacts the childrens longevity and quality of life, and the premature mortality seen in this population is a significant concern ( While initial approaches to treatment involved using lifestyle to manage diabetes, it has become clear that this approach needs supplementation with pharmacotherapy to establish and maintain glycemic control ( Metformin: an ancient drug Metformin is the most widely prescribed pharmacotherapeutic agent to treat T2D globally ( Galega officinalis) , which was used for centuries to treat diabetes (37)

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