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10.1016/j.cell.2013.12.010 59 YangY.TangB

When the body is challenged by pathogens or needs to heal from injuries or surgery, its requirement for vitamin c increases considerably

Androgenetic alopecia affects 30-50% of men by age 50, caused by genetic factors and dihydrotestosterone (DHT) hormone sensitivity Hair loss follows the Hamilton-Norwood classification with seven distinct stages, starting with temple recession and vertex thinning FDA approved treatments include topical minoxidil 2-5% and oral finasteride 1mg daily, which can slow progression and stimulate regrowth Early intervention provides better outcomes hair follicle miniaturization becomes irreversible after arrector pili muscle detachment occurs Hair transplantation using follicular unit extraction or strip harvesting achieves over 90% graft survival rates for permanent restoration Androgenetic alopecia, commonly known as male pattern baldness, represents the most prevalent form of hair loss affecting men worldwide

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