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In TRIUMPH-4, 84% of participants had a baseline BMI of 35 kg/m

Wessely S, Powell R: Fatigue syndromes: a comparison of chronic postviral fatigue with neuromuscular and affective disorders

Leptin is a hormone released by the body to help maintain normal weight and regulate the balance between food intake and energy use, and researchers have identified leptin resistance as one of the main biological contributors to obesity