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Mechanistically, hyperactivation of Drp1 suppresses hexokinase 1 (HK1), a glycolytic enzyme localized to the mitochondria, inducing metabolic reprogramming that promotes NLRP3-driven inflammation and oligodendrocyte pyroptosis (Pradeepkiran and Reddy, 2020

Synergistic Effect (BPC-157 + KPV): When combined, these peptides amplify healing capacity, reduce inflammatory markers, and promote cellular resilience