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Enhanced NK cell activity and a Th1-skewed cytokine profile (marked by elevated IFN- levels) could theoretically heighten the risk of immune overactivation, which is particularly worrisome in individuals with pre-existing autoimmune disorders, where such stimulation may aggravate disease progression [151, 152]

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

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This suggests that glutathione and conventional therapy may have a similar therapeutic impact