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[1] These effects are typically dose-dependent, most pronounced during dose escalation, and tend to diminish over time

Label the vial immediately with three critical data points: (1) reconstitution date, (2) concentration in mg/mL, and (3) expiration date (28 days from reconstitution when stored at 28C)

Decrease dose consideration: Persistent side effects including headaches, fatigue, or injection site reactions, excessive response (extremely rapid weight loss suggesting dose may be higher than needed), cost concerns when lower doses might achieve similar results

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