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doi: 10.3389/fevo.2023.1194611 Received 27 March 2023 Accepted 31 May 2023 Published 28 June 2023 Volume 11 - 2023 Edited by Pavel Stopka, Charles University, Czechia Reviewed by Mousumi Poddar Sarkar, University of Calcutta, India

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Another study revealed that gentamycin induced nephrotoxicity by over-producing of reactive oxygen species and free radicals and significantly increased serum NGAL, KIM-1 and cystatin-c whereas Irbesartan and other angiotensin II blockers reverse this effect and improve renal function through Modulation of oxidative stress and endogenous antioxidant Capacity [57]

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