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This includes appropriate personal protective equipment, clean preparation surfaces, labelled containers, controlled disposal, and accurate record keeping

Enzymatic protein fragmentation can be caused by proteolytic activity of residual or contaminating proteases or in select cases, autoproteolysis of an enzymatic protein (79)

The decrease was not of enough magnitude to have significantly less patients below risk cutoff values (0.24 for AIP, 36 for HSI), although the proportion of those who achieved this goal was higher in the non-CKD group ( Supplementary Figures 2A, C )