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Inhibition of mitochondrial (etomoxir) and peroxisomal (thioridazine) fatty acid oxidation revealed that each organelle contributes to approximately half of acetyl-CoA produced from palmitate in the DKO cells (Supplemental Figure 5G)

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Since idiopathic vitiligo is considered an acquired syndrome, the relevance of the genetic contribution should be taken into account even though the disease is not necessarily inherited by the offspring (Karelson et al