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Current evidence and the Medicines and Healthcare products Regulatory Agency (MHRA) Summary of Product Characteristics indicate that semaglutide does not directly alter potassium homeostasis through its pharmacological action

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A GLP-1 programme for the 2.3 million Canadians who lack any payer for the obesity indication and cannot self-pay would cost approximately $2.2 billion annually in drug costs at generic equilibrium pricing comparable scale, proven administrative architecture