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The only way to be certain of its sterility is to trust the process: refrigerate immediately after first use and discard after 28 days

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In some embodiments, any formulation or composition described herein has a pH that allows for sterilization (e.g., by filtration or aseptic mixing or heat treatment and/or autoclaving (e.g., terminal sterilization)) of a formulation or composition without degradation of the therapeutic agent