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Lower levels of Se cause a decrease in GPx activity [35], increasing the damage caused by free radicals, which contribute to aging and mortality in adults over 65 [36, 37]

In this context, it has been shown that estrogen supplementation positively regulate the transcription of APE1 and NTH1 in the dorsal raphe of OVX old macaques (Dietrich et al., 2013)

Finally, as in our prior study, we also searched the citation records of Google Scholar for all identified full text articles in order to locate in press and pre-print articles that are not yet indexed

Sauna and Stress Response: Resetting the Nervous System Chronic stress is one of the biggest contributors to hormonal imbalances, immune dysfunction, and inflammation