In the double-blinded Metformin to Augment Strength Training Effective Response in Seniors (MASTERS) trial (203), metformin, despite an increase in AMPK signaling, blunted the exercise-induced hypertrophic response in skeletal muscle in healthy men and women over the age of 65 who took part in a supervised progressive resistance exercise training program over 14 weeks following a 2 week metformin treatment (1700 mg/day, or placebo) (203)
Semaglutide is approved by the FDA, but compounded semaglutide isnt
Absolute walk-away red flags: any FDA-approved compounded claim, generic Ozempic or generic Wegovy marketing, a sub-$90 standard-dose price, overseas shipping from China or India, or no physician oversight anywhere in the flow
Garlic, onions, asparagus, bananas, and Jerusalem artichokes are rich prebiotic sources