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The most frequent side effects reported with HS-20094 were decreased appetite and nausea, both of which were considered to be mild to moderate in severity

The Lurcher mouse model, which also shows similarities with CCAS in cognitive impairment and visuomotor impairment, can be used to study disturbances of anatomical and functional connectivity of the cerebellum with the other brain areas

Caution is advised in patients with severe renal impairment mainly due to risk of volume depletion

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