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As reported, RA has an annual incidence of 3 cases/10,000 people and a prevalence of 1% worldwide, with a predilection for women (5)

Moreover, dysregulated lipid metabolism networks such as ACSL/SCD also drive EMT and migratory properties, and their pharmacologic inhibition selectively impairs CRC cell viability, further broadening the landscape of metabolic vulnerabilities in metastatic CRC [96]

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Senza una corretta disponibilit di rame, la pelle tende a perdere elasticit, compattezza e capacit di rigenerazione